TY  -  
T1  - Overcoming Safety and Efficacy Challenges of Adoptive T-Cell Therapy with Cytokine-Coding Oncolytic Adenoviruses 
SN  -  /  
UR  - URN:ISBN:978-951-51-6615-9; http://hdl.handle.net/10138/320155 
T3  -  
A1  - Santos, João Manuel 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2020 
LA  - en 
AB  - The onset of cancer progression is largely mediated by a dysfunctional adaptive immune system which fails to actively eradicate tumor cells. Adding to the demand for viable long-term curative options for advanced or metastatic cancers, immunotherapeutic strategies have been developed with the intent of efficiently restoring antitumor immunity. An approach to achieve the latter consists in the generation and expansion of tumor-specific T-cells for adoptive infusion in cancer patients, in a proces... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - medicine 
N1  -   
PP  -  
ER  -