TY - T1 - Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study SN - / UR - http://hdl.handle.net/10138/312967 T3 - A1 - Peltonen, Sirkku; Kallionpaa, Roope A.; Rantanen, Matti; Uusitalo, Elina; Lähteenmäki, Päivi M.; Pöyhönen, Minna; Pitkäniemi, Janne; Peltonen, Juha A2 - PB - Y1 - 2019 LA - eng AB - Neurofibromatosis type 1 (NF1) is a cancer predisposition syndrome with an incidence of 1:2,000. Patients with NF1 have an increased cancer risk and mortality, but there are no population-based cohort studies specifically investigating the risk of childhood malignancies. We used the Finnish NF1 cohort to analyze the incidence, risk and prognosis of malignancies in NF1 patients... VO - IS - SP - OP - KW - astrocytoma; glioma; leukemia; malignant peripheral nerve sheath tumor; plexiform neurofibroma; NERVE SHEATH TUMORS; CHILDREN; CHILDHOOD; GLIOMAS; MORTALITY; DISEASE; MPNST; RISK; 3122 Cancers N1 - PP - ER -