TY  -  
T1  - Phenotypic effects of dietary stress in combination with a respiratory chain bypass in mice 
SN  -  /  
UR  - http://hdl.handle.net/10138/306009 
T3  -  
A1  - Dhandapani, Praveen K.; Lyyski, Annina M.; Paulin, Lars; Khan, Nahid A.; Suomalainen, Anu; Auvinen, Petri; Dufour, Eric; Szibor, Marten; Jacobs, Howard T. 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - The alternative oxidase (AOX) from Ciona intestinalis was previously shown to be expressible in mice and to cause no physiological disturbance under unstressed conditions. Because AOX is known to become activated under some metabolic stress conditions, resulting in altered energy balance, we studied its effects in mice subjected to dietary stress. Wild-type mice (Mus musculus, strain C57BL/6JOlaHsd) fed a high-fat or ketogenic (high-fat, low-carbohydrate) diet show weight gain with increased fat... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - mitochondria; obesity; respiratory chain; high-fat diet; ketogenic diet; microbiome; ALTERNATIVE-OXIDASE; BODY-WEIGHT; HIGH-FAT; GUT MICROBIOME; EXPRESSION; OBESITY; MITOCHONDRIA; DROSOPHILA; MODEL; GENETICS; 1184 Genetics, developmental biology, physiology 
N1  -   
PP  -  
ER  -