TY  -  
T1  - Platelet-derived growth factor stimulates Src-dependent mRNA stabilization of specific early genes in fibroblasts. 
SN  -  /  
UR  - http://hdl.handle.net/10138/33909 
T3  -  
A1  - Bromann, Paul Andrew; Korkaya, Hasan; Webb, Craig P.; Miller, Jeremy; Calvin, Tammy L.; Courtneidge, Sara A. 
A2  -  
PB  -  
Y1  - 2005 
LA  - eng 
AB  - The Src family of protein-tyrosine kinases (SFKs) participates in a variety of signal transduction pathways, including promotion of cell growth, prevention of apoptosis, and regulation of cell interactions and motility. In particular, SFKs are required for the mitogenic response to platelet-derived growth factor (PDGF). However, it is not clear whether there is a discrete SFK-specific pathway leading to enhanced gene expression or whether SFKs act to generally enhance PDGF-stimulated gene expres... 
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OP  -  
KW  - 113 Computer and information sciences; BIOINFORMATICS; 3111 Biomedicine; DRUG DISCOVERY; 317 Pharmacy; INHIBITORS; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -