TY  -  
T1  - PockDrug-Server : a new web server for predicting pocket druggability on holo and apo proteins 
SN  -  /  
UR  - http://hdl.handle.net/10138/161953 
T3  -  
A1  - Hussein, Hiba Abi; Borrel, Alexandre; Geneix, Colette; Petitjean, Michel; Regad, Leslie; Camproux, Anne-Claude 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - Predicting protein pocket's ability to bind drug-like molecules with high affinity, i.e. druggability, is of major interest in the target identification phase of drug discovery. Therefore, pocket druggability investigations represent a key step of compound clinical progression projects. Currently computational druggability prediction models are attached to one unique pocket estimation method despite pocket estimation uncertainties. In this paper, we propose 'PockDrug-Server' to predict pocket dr... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - BINDING-SITES; DRUG DISCOVERY; PATHWAY; DESIGN; MODEL; 317 Pharmacy; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -