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T1  - Polygenic Risk Score of SERPINA6/SERPINA1 Associates with Diurnal and Stress-Induced HPA Axis Activity in Children 
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UR  - http://hdl.handle.net/10138/300875 
T3  -  
A1  - Utge, Siddheshwar; Räikkönen, Katri; Kajantie, Eero; Lipsanen, Jari; Andersson, Sture; Strandberg, Timo; Reynolds, Rebecca M.; Eriksson, Johan G.; Lahti, Jari 
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Y1  - 2018 
LA  - eng 
AB  - Purpose: Corticosteroid-binding globulin (CBG) transports glucocorticoids in blood. Variation in genes SERPINA6 encoding for CBG, SERPINA2 and SERPINAI (serpin family A member 6, 2, and 1) have been shown to influence morning plasma cortisol and CBG in adults. However, association of this genetic variation with diurnal and stress-induced salivary cortisol remain unknown. This study aims to investigate the effect of genetic variation in SERPINA6/2/1 loci on diurnal and stress-induced salivary cor... 
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KW  - Polygenic risk score (PRS); SERPINA6; SERPINA2; SERPINA1; Salivary cortisol; Stress; CORTICOSTEROID-BINDING GLOBULIN; LICORICE CONSUMPTION; PSYCHOSOCIAL STRESS; CORTISOL RESPONSE; SALIVARY CORTISOL; GENE; HORMONE; FATIGUE; GLUCOCORTICOIDS; POLYMORPHISMS; 515 Psychology 
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