TY  -  
T1  - Prediction of neo-adjuvant chemotherapy response in bladder cancer : the impact of clinical parameters and routine biomarkers 
SN  -  /  
UR  - http://hdl.handle.net/10138/339481 
T3  -  
A1  - Koskinen, Ilmari; Boström, Peter J.; Taimen, P.; Salminen, A.; Tervahartiala, M.; Sairanen, J.; Erickson, A.; Mirtti, T. 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Purpose To investigate the role of clinical parameters and immunohistochemical (IHC) biomarkers in their feasibility to predict the effect of neo-adjuvant chemotherapy (NAC) in patients with muscle-invasive urothelial bladder cancer (MIBC). Materials and methods The first 76 consecutive patients with MIBC treated with NAC and radical cystectomy in two University hospitals in Finland between 2008 and 2013 were chosen for this study. After excluding patients with non-urothelial cancer, less than t... 
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KW  - Muscle-invasive bladder cancer; neo-adjuvant chemotherapy; cystectomy; immunohistochemistry; TRANSITIONAL-CELL CARCINOMA; RADICAL CYSTECTOMY; P53; EXPRESSION; OVEREXPRESSION; CISPLATIN; AMPLIFICATION; METHOTREXATE; VINBLASTINE; DOXORUBICIN; 3122 Cancers; 3126 Surgery, anesthesiology, intensive care, radiology 
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ER  -