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T1  - Predictive value of childhood airway hyperresponsiveness to indirect stimuli: 10-year longitudinal study 
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UR  - http://hdl.handle.net/10138/328202 
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A1  - Lajunen, Katariina Tytti; Malmberg, Leo Pekka; Kalliola, Satu; Kotaniemi-Syrjänen, Anne; Pelkonen, L. Anna Susanna; Mäkelä, Mika Juhani 
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Y1  - 2020 
LA  - eng 
AB  - Abstract Background Airway hyperresponsiveness (AHR) is a common feature in asthma. The use of AHR in predicting active asthma or the persistence of AHR in childhood is poorly understood. By analyzing longitudinal connections including different measures of AHR, lung function, and inflammation markers, we sought to identify the best available method for predicting persistence of AHR and identification of later active asthma. Methods We tested 105 asthmatic children aged 3-7 years with fractional... 
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KW  - 3123 Gynaecology and paediatrics; Airway hyper-responsiveness; Ashtma; Childhood; Lung function; Methacholine challenge; Prospective; BRONCHIAL HYPERRESPONSIVENESS; RESPIRATORY SYMPTOMS; LUNG-FUNCTION; ASTHMA; CHILDREN; AGE; RESPONSIVENESS; DETERMINANTS; IMPEDANCE; 3121 General medicine, internal medicine and other clinical medicine 
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