TY  -  
T1  - Presence of Stromal Cells Enhances Epithelial-to-Mesenchymal Transition (EMT) Induction in Lung Bronchial Epithelium after Protracted Exposure to Oxidative Stress of Gamma Radiation 
SN  -  /  
UR  - http://hdl.handle.net/10138/305932 
T3  -  
A1  - Acheva, Anna; Haghdoost, Siamak; Sollazzo, Alice; Launonen, Virpi; Kämäräinen, Meerit 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - The aim of the study was to investigate the role of a microenvironment in the induction of epithelial-to-mesenchymal transition (EMT) as a sign of early stages of carcinogenesis in human lung epithelial cell lines after protracted low-dose rate gamma-radiation exposures. BEAS-2B and HBEC-3KT lung cell lines were irradiated with low-dose rate gamma-rays (Cs-137, 1.4 or 14 mGy/h) to 0.1 or 1 Gy with or without adding TGF-beta. TGF-beta-treated samples were applied as positive EMT controls and test... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - CANCER-ASSOCIATED FIBROBLASTS; TGF-BETA; NUCLEOTIDE POOL; TUMOR-GROWTH; ACTIVATION; MICROENVIRONMENT; CARCINOGENESIS; MECHANISMS; 8-OXO-DG; TARGET; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -