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T1  - Pretargeted PET imaging of porous silicon nanoparticles and monoclonal antibodies : Development of 18F-fluoroglycosylated tetrazine tracer for the Iedda reaction in vivo 
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UR  - URN:ISBN:978-951-51-4528-4; http://hdl.handle.net/10138/242103 
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A1  - Keinänen, Outi 
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PB  - Helsingin yliopisto 
Y1  - 2018 
LA  - eng 
AB  - Positron emission tomography (PET) is a sensitive and quantitative molecular imaging method. Nowadays PET is widely used in the clinic, and increasingly in drug discovery and development. In pretargeted PET imaging, the targeting moiety, such as an antibody or a nanoparticle, is first let to localize and bind to its target and any excess is allowed to clear from the body before radiolabeling in vivo. The radiolabeling proceeds rapidly at the target site when the secondarily administered radiotra... 
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