TY  -  
T1  - Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali : a single-blind, dose-ranging, adaptive randomised phase 2 trial 
SN  -  /  
UR  - http://hdl.handle.net/10138/224035 
T3  -  
A1  - Dicko, Alassane; Brown, Joelle M.; Diawara, Halimatou; Baber, Ibrahima; Mahamar, Almahamoudou; Soumare, Harouna M.; Sanogo, Koualy; Koita, Fanta; Keita, Sekouba; Traore, Sekou F.; Chen, Ingrid; Poirot, Eugenie; Hwang, Jimee; McCulloch, Charles; Lanke, Kjerstin; Pett, Helmi; Niemi, Mikko; Nosten, Francois; Bousema, Tevn; Gosling, Roly 
A2  -  
PB  -  
Y1  - 2016 
LA  - eng 
AB  - Background Single low doses of primaquine, when added to artemisinin-based combination therapy, might prevent transmission of Plasmodium falciparum malaria to mosquitoes. We aimed to establish the activity and safety of four low doses of primaquine combined with dihydroartemisinin-piperaquine in male patients in Mali. Methods In this phase 2, single-blind, dose-ranging, adaptive randomised trial, we enrolled boys and men with uncomplicated P falciparum malaria at the Malaria Research and Trainin... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - DIHYDROARTEMISININ-PIPERAQUINE; G6PD DEFICIENCY; GAMETOCYTES; AFRICA; QUANTIFICATION; CLEARANCE; RESPONSES; CHILDREN; SAFETY; FEMALE; 3121 General medicine, internal medicine and other clinical medicine 
N1  -   
PP  -  
ER  -