TY  -  
T1  - Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp CENA543 
SN  -  /  
UR  - http://hdl.handle.net/10138/231314 
T3  -  
A1  - Jokela, Jouni; Heinilä, Lassi M. P.; Shishido, Tania K.; Wahlsten, Matti; Fewer, David P.; Fiore, Marli F.; Wang, Hao; Haapaniemi, Esa; Permi, Perttu; Sivonen, Kaarina 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Nostoc is a cyanobacterial genus, common in soils and a prolific producer of natural products. This research project aimed to explore and characterize Brazilian cyanobacteria for new bioactive compounds. Here we report the production of hepatotoxins and new protease inhibitors from benthic Nostoc sp. CENA543 isolated from a small, shallow, saline-alkaline lake in the Nhecolandia, Pantanal wetland area in Brazil. Nostoc sp. CENA543 produces exceptionally high amounts of nodularin-R. This is the f... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - cyanobacteria; Nostoc; nodularin; spumigin; biosynthesis; SALINE-ALKALINE LAKES; CYANOBACTERIUM NODULARIA; BALTIC SEA; SPUMIGENA; PEPTIDES; DIVERSITY; TOXIN; SPECIFICITY; PREDICTION; EVOLUTION; 1183 Plant biology, microbiology, virology 
N1  -   
PP  -  
ER  -