TY  -  
T1  - Prostaglandin E-2-EP2-NF-kappa B signaling in macrophages as a potential therapeutic target for intracranial aneurysms 
SN  -  /  
UR  - http://hdl.handle.net/10138/233572 
T3  -  
A1  - Aoki, Tomohiro; Frösen, Juhana; Fukuda, Miyuki; Bando, Kana; Shioi, Go; Tsuji, Keiichi; Ollikainen, Eliisa; Nozaki, Kazuhiko; Laakkonen, Johanna; Narumiya, Shuh 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Intracranial aneurysms are common but are generally untreated, and their rupture can lead to subarachnoid hemorrhage. Because of the poor prognosis associated with subarachnoid hemorrhage, preventing the progression of intracranial aneurysms is critically important. Intracranial aneurysms are caused by chronic inflammation of the arterial wall due to macrophage infiltration triggered by monocyte chemoattractant protein-1 (MCP-1), macrophage activation mediated by the transcription factor nuclear... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - NF-KAPPA-B; CEREBRAL ANEURYSMS; SUBARACHNOID HEMORRHAGE; CHRONIC INFLAMMATION; RECEPTOR ANTAGONIST; RUPTURE; WALL; ACTIVATION; ASPIRIN; CELLS; 1182 Biochemistry, cell and molecular biology; 3111 Biomedicine 
N1  -   
PP  -  
ER  -