TY  -  
T1  - Proteochemometric Modeling of the Antigen-Antibody Interaction : New Fingerprints for Antigen, Antibody and Epitope-Paratope Interaction 
SN  -  /  
UR  - http://hdl.handle.net/10138/160349 
T3  -  
A1  - Qiu, Tianyi; Xiao, Han; Zhang, Qingchen; Qiu, Jingxuan; Yang, Yiyan; Wu, Dingfeng; Cao, Zhiwei; Zhu, Ruixin 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - Despite the high specificity between antigen and antibody binding, similar epitopes can be recognized or cross-neutralized by paratopes of antibody with different binding affinities. How to accurately characterize this slight variation which may or may not change the antigen-antibody binding affinity is a key issue in this area. In this report, by combining cylinder model with shell structure model, a new fingerprint was introduced to describe both the structural and physical-chemical features o... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - PROTEIN-BINDING SITES; CRYSTAL-STRUCTURE; SPACE; RECOGNITION; PREDICTION; INHIBITORS; INTERFACE; ALIGNMENT; PATTERNS; SURFACES; 113 Computer and information sciences 
N1  -   
PP  -  
ER  -