TY  -  
T1  - Pullulan Based Bioconjugates for Ocular Dexamethasone Delivery 
SN  -  /  
UR  - http://hdl.handle.net/10138/332742 
T3  -  
A1  - Kickova, Eva; Salmaso, Stefano; Mastrotto, Francesca; Caliceti, Paolo; Urtti, Arto 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Posterior segment eye diseases are mostly related to retinal pathologies that require pharmacological treatments by invasive intravitreal injections. Reduction of frequent intravitreal administrations may be accomplished with delivery systems that provide sustained drug release. Pullulan-dexamethasone conjugates were developed to achieve prolonged intravitreal drug release. Accordingly, dexamethasone was conjugated to similar to 67 kDa pullulan through hydrazone bond, which was previously found ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - pullulan; dexamethasone; hydrazone; ocular drug delivery; controlled release; DRUG-DELIVERY; CONTROLLED-RELEASE; NANOPARTICLE; PH; DOXORUBICIN; LINKERS; IMPLANT; BARRIER; 317 Pharmacy 
N1  -   
PP  -  
ER  -