TY - T1 - Quantitative changes in perineuronal nets in development and posttraumatic condition SN - / UR - http://hdl.handle.net/10138/303716 T3 - A1 - Lipachev, Nikita; Arnst, Nikita; Melnikova, Anastasiia; Jäälinoja, Harri; Kochneva, Anastasiya; Zhigalov, Alexander; Kulesskaya, Natalia; Aganov, Albert V.; Mavlikeev, Mikhail; Rauvala, Heikki; Kiyasov, Andrey P.; Paveliev, Mikhail A2 - PB - Y1 - 2019 LA - eng AB - Perineuronal net (PNN) is a highly structured portion of the CNS extracellular matrix (ECM) regulating synaptic plasticity and a range of pathologic conditions including posttraumatic regeneration and epilepsy. Here we studied Wisteria floribunda agglutinin-stained histological sections to quantify the PNN size and enrichment of chondroitin sulfates in mouse brain and spinal cord. Somatosensory cortex sections were examined during the period of PNN establishment at postnatal days 14, 21 and 28. ... VO - IS - SP - OP - KW - 3112 Neurosciences; Perineuronal nets; Extracellular matrix; Somatosensory cortex; Brain development; Spinal cord injury; CHONDROITIN SULFATE PROTEOGLYCANS; SPINAL-CORD-INJURY; EXTRACELLULAR-MATRIX; FUNCTIONAL REGENERATION; TENASCIN-R; PLASTICITY; EXPRESSION; GROWTH; MOUSE; HYALURONAN N1 - PP - ER -