TY - T1 - RRx-001 Priming of PD-1 Inhibition in the Treatment of Small Cell Carcinoma of the Vagina : A Rare Gynecological Tumor SN - / UR - http://hdl.handle.net/10138/299311 T3 - A1 - Brzezniak, Christina; Oronsky, Bryan; Trepel, Jane; Summers, Thomas A.; Cabrales, Pedro; Lee, Min-Jung; Day, Regina; Jha, Saheli; Caroen, Scott; Zeman, Karen; Ferry, Lindsey; Harmer, Cindy; Oronsky, Neil; Lybeck, Michelle; Lybeck, Harry E.; Brown, James F.; Reid, Tony R.; Carter, Corey A. A2 - PB - Y1 - 2017 LA - eng AB - Small cell carcinoma of the vagina is rare, so rare in fact that the total number reported in English-language journals is less than 30. Due to this extremely low incidence, no specific treatment guidelines have been established, and most of what is clinically known is derived from a handful of single case reports. However, as befitting its highly aggressive histologic features, which are reminiscent of small cell lung cancer (SCLC), first-line treatment is modeled after SCLC. Herein is reported... VO - IS - SP - OP - KW - Small cell carcinoma; Vagina; Tumor-associated macrophage stimulation; Immunotherapy; Chemotherapy; Pseudoprogression; RRx-001; PSEUDOPROGRESSION; PATIENT; 3122 Cancers N1 - PP - ER -