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T1  - Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor 
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UR  - http://hdl.handle.net/10138/324004 
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A1  - Zheng, Guoqiao; Sundquist, Kristina; Sundquist, Jan; Försti, Asta; Hemminki, Akseli; Hemminki, Kari 
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Y1  - 2020 
LA  - eng 
AB  - Background Many cancers are increased in immunosuppressed patients and evidence is accumulating that immune dysfunction may be a contributing risk factor for second primary cancers (SPCs). The aim of this study was to explore the potential influence of immune mechanisms in SPC. Methods We used the Swedish Cancer Registry (1990-2015) to select 13 male and 14 female first primary cancers (FPCs) that are known to be related to immune suppression. We assessed relative risks (RRs) for any of these as... 
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KW  - cancer risk; immune suppression; multiple cancers; risk factors; TRANSPLANTATION; INFLAMMATION; LYMPHOMA; 3122 Cancers 
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