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T1  - Regulation of the Muscarinic M-3 Receptor by Myocardin-Related Transcription Factors 
SN  -  /  
UR  - http://hdl.handle.net/10138/335928 
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A1  - Liu, Li; Rippe, Catarina; Hansson, Ola; Kryvokhyzha, Dmytro; Fisher, Steven; Ekman, Mari; Sward, Karl 
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PB  -  
Y1  - 2021 
LA  - eng 
AB  - Myocardin-related transcription factors (MRTFs: myocardin/MYOCD, MRTF-A/MRTFA, and MRTF-B/MRTFB) are co-factors of serum response factor (SRF) that activate the smooth muscle cell (SMC) gene program and that play roles in cardiovascular development and mechanobiology. Gain and loss of function experiments have defined the SMC gene program under control of MRTFs, yet full understanding of their impact is lacking. In the present study, we tested the hypothesis that the muscarinic M-3 receptor (CHR... 
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KW  - cholinergic neurotransmission; pharmacology; acetylcholine; signaling; vasodilatation; SERUM RESPONSE FACTOR; VASCULAR SMOOTH-MUSCLE; ACETYLCHOLINE-RECEPTOR; MICE LACKING; ENDOTHELIAL-CELLS; GENE-EXPRESSION; SRF; DIFFERENTIATION; INACTIVATION; DISRUPTION; 1184 Genetics, developmental biology, physiology 
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