TY - T1 - Relation of cholesterol metabolism to pediatric gallstone disease : a retrospective controlled study SN - / UR - http://hdl.handle.net/10138/164069 T3 - A1 - Koivusalo, Antti; Pakarinen, Mikko; Gylling, Helena; Nissinen, Markku J. A2 - PB - Y1 - 2015 LA - eng AB - Background: Cholesterol metabolism may be involved in pediatric gallstone disease. We aimed to reveal cholesterol metabolites and phytosterols and their relation to stone composition of sterols in children having black pigment and cholesterol stones. Methods: We performed retrospective controlled clinical study, in which we examined parameters of cholesterol metabolism and liver function values in serum (n = 28) and gallstones (n = 46) of consecutively cholecystectomized children. Serum values o... VO - IS - SP - OP - KW - Black pigment gallstones; Cholesterol gallstones; Non-cholesterol sterols; Plant sterols; NUCLEAR RECEPTOR FXR; SERUM PLANT STEROLS; SURROGATE MARKERS; NONCHOLESTEROL STEROLS; PIGMENT GALLSTONES; ABSORPTION; GALLBLADDER; CHILDREN; BILE; BIOSYNTHESIS; 3123 Gynaecology and paediatrics; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -