TY - T1 - Resection of colorectal liver metastases after second-line chemotherapy : is it worthwhile? A LiverMetSurvey analysis of 6415 patients SN - / UR - http://hdl.handle.net/10138/236228 T3 - A1 - Adam, Rene; Yi, Bin; Innominato, Pasquale F.; Barroso, Eduardo; Laurent, Christophe; Giuliante, Felice; Capussotti, Lorenzo; Lapointe, Real; Regimbeau, Jean-Marc; Lopez-Ben, Santiago; Isoniemi, Helena; Hubert, Catherine; Lin, Jen-Kou; Gruenberger, Thomas; Elias, Dominique; Skipenko, Oleg G.; Guglielmi, Alfredo; LiverMetSurvey Int Contributing A2 - PB - Y1 - 2017 LA - eng AB - Purpose: Patient outcome after resection of colorectal liver metastases (CLM) following second-line preoperative chemotherapy (PCT) performed for insufficient response or toxicity of the first-line, is little known and has here been compared to the outcome following first-line. Patients and methods: From January 2005 to June 2013, 5624 and 791 consecutive patients of a prospective international cohort received 1 and 2 PCT lines before CLM resection (group 1 and 2, respectively). Survival and pro... VO - IS - SP - OP - KW - Colorectal cancer; Liver metastasis; Preoperative chemotherapy; Second line; Hepatectomy; LONG-TERM SURVIVAL; SYSTEMIC CHEMOTHERAPY; PHASE-II; CANCER; OXALIPLATIN; INFUSION; TRIAL; 5-FLUOROURACIL; PROGRESSION; LEUCOVORIN; 3122 Cancers N1 - PP - ER -