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T1  - Resveratrol supplementation at old age reverts changes associated with aging in inflammatory, oxidative and apoptotic markers in rat heart 
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UR  - http://hdl.handle.net/10138/340114 
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A1  - Torregrosa-Munumer, Ruben; Vara, Elena; Fernandez-Tresguerres, Jesus Angel; Gredilla, Ricardo 
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Y1  - 2021 
LA  - eng 
AB  - Purpose Aging is known to play a critical role in the etiopathogenesis of several diseases. Among them, cardiovascular disorders are especially relevant since they are becoming the first cause of death in western countries. Resveratrol is a polyphenolic compound that has been shown to exert beneficial effects at different levels, including neuronal and cardiovascular protection. Those effects of resveratrol are related, at least in part, to its antioxidant and anti-inflammatory properties. In th... 
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KW  - Resveratrol; Aging; Heart; Inflammation; Oxidation; Apoptosis; NITRIC-OXIDE SYNTHASE; TERM CALORIC RESTRICTION; FACTOR-KAPPA-B; ENDOTHELIAL DYSFUNCTION; CARDIOVASCULAR HEALTH; CARDIAC DYSFUNCTION; SIRT1 ACTIVATION; GENE-EXPRESSION; CELL-DEATH; STRESS; 3143 Nutrition 
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