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T1  - Role of Damage Associated Molecular Pattern Molecules (DAMPs) in Aneurysmal Subarachnoid Hemorrhage (aSAH) 
SN  -  /  
UR  - http://hdl.handle.net/10138/237843 
T3  -  
A1  - Chaudhry, Shafqat Rasul; Hafez, Ahmad; Rezai Jahromi, Behnam; Kinfe, Thomas Mehari; Lamprecht, Alf; Niemelä, Mika; Muhammad, Sajjad 
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PB  -  
Y1  - 2018 
LA  - eng 
AB  - Aneurysmal subarachnoid hemorrhage (aSAH) represents only a small portion of all strokes, but accounts for almost half of the deaths caused by stroke worldwide. Neurosurgical clipping and endovascular coiling can successfully obliterate the bleeding aneurysms, but ensuing complications such as cerebral vasospasm, acute and chronic hydrocephalus, seizures, cortical spreading depression, delayed ischemic neurological deficits, and delayed cerebral ischemia lead to poor clinical outcomes. The mecha... 
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KW  - 3112 Neurosciences; 3124 Neurology and psychiatry; 3126 Surgery, anesthesiology, intensive care, radiology; subarachnoid hemorrhage; danger associated molecular pattern molecules (DAMPs); alarmins; high mobility group box-1 (HMGB1); S100B; mitochondrial DNA; hemoglobin; interleukin (IL)-33; IL-1 alpha; heat shock proteins; TOLL-LIKE RECEPTORS; GROUP BOX 1; DELAYED CEREBRAL-ISCHEMIA; BASILAR ARTERY VASOSPASM; MITOCHONDRIAL-DNA LEVELS; INNATE IMMUNE-RESPONSES; CENTRAL-NERVOUS-SYSTEM; EARLY BRAIN-INJURY; CEREBROSPINAL-FLUID; S-100 PROTEIN 
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