TY - T1 - Role of dehydroepiandrosterone in high-density lipoprotein-mediated vasodilation and in adipose tissue steroid biosynthesis SN - / UR - URN:ISBN:978-951-51-2102-8; http://hdl.handle.net/10138/162809 T3 - A1 - Paatela, Hanna A2 - PB - Helsingin yliopisto Y1 - 2016 LA - eng AB - Dehydroepiandrosterone (DHEA) and its sulfate ester DHEA sulfate (DHEAS) are the most abundant steroid hormones in the circulation. These prohormones, secreted by the adrenal glands, are important precursors of biologically active androgens and estrogens. Adipose tissue is an important site for estrogen synthesis after menopause, when all estrogens are produced from hormone precursors in peripheral tissues. In the circulation, DHEA exists also as fatty acyl esters. These lipophilic derivatives o... VO - IS - SP - OP - KW - lääketiede N1 - PP - ER -