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T1  - Role of the Neuregulin Signaling Pathway in Nicotine Dependence and Co-morbid Disorders 
SN  -  /  
UR  - http://hdl.handle.net/10138/224172 
T3  - International Review of Neurobiology 
A1  - Fisher, Miranda L.; Loukola, Anu; Kaprio, Jaakko; Turner, Jill R. 
A2  - DeBiasi, Mariella 
PB  - ACADEMIC PRESS INC ELSEVIER SCIENCE 
Y1  - 2015 
LA  - eng 
AB  - Smoking is currently the leading cause of preventable death in the United States and is responsible for over four million deaths annually worldwide. Therefore, there is a vast clinical unmet need with regards to therapeutics targeting smoking cessation. This is even more apparent when examining smokers co-morbid with psychiatric illness, as rates of smoking in this population are similar to 4 x higher than in the general population. Examining common genetic and molecular signaling pathways impin... 
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KW  - SUSTAINED-RELEASE BUPROPION; RANDOMIZED CONTROLLED-TRIAL; RECEPTOR TYROSINE KINASE; SMOKING-CESSATION; CIGARETTE-SMOKING; SUSCEPTIBILITY LOCI; MAJOR DEPRESSION; BIPOLAR DISORDER; PARTIAL AGONIST; NERVOUS-SYSTEM; 3112 Neurosciences; 3124 Neurology and psychiatry; 3142 Public health care science, environmental and occupational health 
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