TY  -  
T1  - Scopolamine effects on functional brain connectivity : a pharmacological model of Alzheimer's disease 
SN  -  /  
UR  - http://hdl.handle.net/10138/162447 
T3  -  
A1  - Bajo, R.; Pusil, S.; Lopez, M. E.; Canuet, L.; Pereda, E.; Osipova, D.; Maestu, F.; Pekkonen, E. 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - Scopolamine administration may be considered as a psychopharmacological model of Alzheimer's disease (AD). Here, we studied a group of healthy elderly under scopolamine to test whether it elicits similar changes in brain connectivity as those observed in AD, thereby verifying a possible model of AD impairment. We did it by testing healthy elderly subjects in two experimental conditions: glycopyrrolate (placebo) and scopolamine administration. We then analyzed magnetoencephalographic (MEG) data c... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - MILD COGNITIVE IMPAIRMENT; DIFFUSION-WEIGHTED MRI; EEG SYNCHRONIZATION; HEALTHY-VOLUNTEERS; GRAPH-THEORY; MEMORY TASK; COHERENCE; ELECTROENCEPHALOGRAM; NETWORKS; DYNAMICS; 3112 Neurosciences; 3124 Neurology and psychiatry 
N1  -   
PP  -  
ER  -