TY - T1 - Search for Susceptibility Genes in Osteoarthritis SN - / UR - URN:ISBN:978-952-245-615-1; http://hdl.handle.net/10138/30205 T3 - A1 - Näkki, Annu A2 - PB - Helsingin yliopisto Y1 - 2012 LA - en AB - Osteoarthritis (OA) is a complex disease characterized by the destruction of the articular cartilage of the joints. The main symptoms are pain and disability, caused most probably by secondary synovitis. Secondary manifestations of OA are considered to be bone changes, osteophytes, subchondral sclerosis, and bone cysts. The suspected risk factors for OA include genetic predisposition, gender (greater in females), old age, obesity (also in non-weight-bearing joints), previous injury and various p... VO - IS - SP - OP - KW - lääketiede, genetiikka N1 - PP - ER -