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T1  - Second-Trimester Placental and Thyroid Hormones Are Associated With Cognitive Development From Ages 1 to 3 Years 
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UR  - http://hdl.handle.net/10138/335086 
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A1  - Adibi, JJ; Xun, XS; Zhao, YQ; Yin, Q; LeWinn, K; Bush, NR; Panigrahy, A; Peddada, S; Alfthan, H; Stenman, UH; Tylavsky, F; Koistinen, H 
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Y1  - 2021 
LA  - eng 
AB  - Adequate maternal thyroid hormone (TH) is necessary for fetal brain development. The role of placental human chorionic gonadotropin (hCG) in ensuring the production of TH is less well understood. The objective of the study was to evaluate 1) associations of placental hCG and its subunits, and maternal TH in the second trimester, and 2) the single and joint effects of TH and placental hormones on cognitive development and communication at ages 1 and 3 years. Fifty individuals (5%) were selected f... 
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KW  - epidemiology; interaction; thyroid; human chorionic gonadotropin; hCG-alpha; Bayley scales; HUMAN CHORIONIC-GONADOTROPIN; FREE ALPHA-SUBUNIT; BETA-SUBUNIT; FETAL SEX; HUMAN-PREGNANCY; SERUM; POPULATION; CHILDHOOD; WEIGHT; BRAIN; 3121 General medicine, internal medicine and other clinical medicine 
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