TY - T1 - Serum Plant Sterols Associate with Gallstone Disease Independent of Weight Loss and Non-Alcoholic Fatty Liver Disease SN - / UR - http://hdl.handle.net/10138/236800 T3 - A1 - Kakela, Pirjo; Mannisto, Ville; Ilves, Imre; Vaittinen, Maija; Tauriainen, Milla-Maria; Eskelinen, Matti; Gylling, Helena; Paajanen, Hannu; Pihlajamaki, Jussi A2 - PB - Y1 - 2017 LA - eng AB - Gallstone disease (GD) has been associated with low serum levels of plant sterols. We evaluated the impact of laparoscopic Roux-en-Y gastric bypass (LRYGB) and non-alcoholic fatty liver disease (NAFLD) on the association of GD with low levels of serum plant sterols. Two hundred forty-two consecutive morbidly obese patients were recruited to this prospective study. Histological analysis of liver biopsy to diagnose NAFLD was performed. Bile sample was taken during the LRYGB. Associations of GD wit... VO - IS - SP - OP - KW - Laparoscopic roux-en-Y gastric bypass; Obesity; Statins; Gallstones; Weight loss; Plant sterols; BILIARY CHOLESTEROL SECRETION; ABSORPTION; ABCG8; RISK; CHOLECYSTECTOMY; STEATOHEPATITIS; TRANSPORTERS; EXPRESSION; SPECTRUM; THERAPY; 3121 General medicine, internal medicine and other clinical medicine; 3126 Surgery, anesthesiology, intensive care, radiology N1 - PP - ER -