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T1  - Serum fasting GLP-1 and GLP-2 associate with intestinal adaptation in pediatric onset intestinal failure 
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UR  - http://hdl.handle.net/10138/298048 
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A1  - Mutanen, Annika; Pakarinen, Mikko P. 
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Y1  - 2017 
LA  - eng 
AB  - Aim: Glukagon-like-peptide-1 (GLP-1) and -2 (GLP-2), produced by intestinal L-cells, are key hormones regulating intestinal transit, secretion, absorption, and mucosal growth. We evaluated nai ve fasting serum GLP-1 and GLP-2 levels in pediatric intestinal failure (IF). Methods: Fifty-five IF patients with median age 4.2 (IQR 1.3-12) years and 47 matched healthy controls underwent measurement of fasting serum GLP-1 and GLP-2. Results: Serum GLP-2 [19.9 (13.8-27.9) vs 11.6 (7.0-18.6) ng/mL, P <0.... 
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KW  - Parenteral nutrition; Short bowel syndrome; Children; SHORT-BOWEL SYNDROME; GLUCAGON-LIKE PEPTIDE-2; PARENTERAL-NUTRITION; TEDUGLUTIDE; CHILDREN; CHOLESTASIS; ABSORPTION; OUTCOMES; 3123 Gynaecology and paediatrics 
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