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T1  - Serum metabolite profiling yields insights into health promoting effect of A. muciniphila in human volunteers with a metabolic syndrome 
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UR  - http://hdl.handle.net/10138/337653 
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A1  - Depommier, Clara; Everard, Amandine; Druart, Celine; Maiter, Dominique; Thissen, Jean-Paul; Loumaye, Audrey; Hermans, Michel P.; Delzenne, Nathalie M.; de Vos, Willem M.; Cani, Patrice D. 
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Y1  - 2021 
LA  - eng 
AB  - Reduction of A. muciniphila relative abundance in the gut microbiota is a widely accepted signature associated with obesity-related metabolic disorders. Using untargeted metabolomics profiling of fasting plasma, our study aimed at identifying metabolic signatures associated with beneficial properties of alive and pasteurized A. muciniphila when administrated to a cohort of insulin-resistant individuals with metabolic syndrome. Our data highlighted either shared or specific alterations in the met... 
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KW  - A; muciniphila; human; obesity; metabolic syndrome; prediabetes; metabolomic; amino-acids; ketone bodies; acylcarnitines; HUMAN GUT MICROBIOME; AKKERMANSIA-MUCINIPHILA; INSULIN-RESISTANCE; ACID-METABOLISM; KETOGENIC DIET; OBESITY; OVERWEIGHT; CONTRIBUTE; RISK; 3121 General medicine, internal medicine and other clinical medicine; 11832 Microbiology and virology 
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