TY  -  
T1  - Sex-related differences in murine hepatic transcriptional and proteomic responses to TCDD 
SN  -  /  
UR  - http://hdl.handle.net/10138/203426 
T3  -  
A1  - Prokopec, Stephenie D.; Watson, John D.; Lee, Jamie; Pohjanvirta, Raimo; Boutros, Paul C. 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an environmental contaminant that produces myriad toxicities in most mammals. In rodents alone, there is a huge divergence in the toxicological response across species, as well as among different strains within a species. But there are also significant differences between males and females animals of a single strain. These differences are inconsistent across model systems: the severity of toxicity is greater in female rats than males, while male mice... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Aryl hydrocarbon receptor; Computational biology; 2,3,7,8-Tetrachlorodibenzo-p-dioxin; TCDD; AH receptor; Sex differences; ARYL-HYDROCARBON RECEPTOR; RESISTANT RAT STRAIN; CONSTITUTIVE ANDROSTANE RECEPTOR; GENE-EXPRESSION PROFILES; SPRAGUE-DAWLEY RATS; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN TCDD; NUCLEAR RECEPTOR; MOUSE-LIVER; TOXICOGENOMIC ANALYSIS; CYTOCHROME-P450 GENES; 413 Veterinary science 
N1  -   
PP  -  
ER  -