TY  -  
T1  - Sex-specific association between infant caudate volumes and a polygenic risk score for major depressive disorder 
SN  -  /  
UR  - http://hdl.handle.net/10138/320824 
T3  -  
A1  - Acosta, Henriette; Kantojarvi, Katri; Tuulari, Jetro J.; Lewis, John D.; Hashempour, Niloofar; Scheinin, Noora M.; Lehtola, Satu J.; Fonov, Vladimir S.; Collins, D. Louis; Evans, Alan; Parkkola, Riitta; Lähdesmäki, Tuire; Saunavaara, Jani; Merisaari, Harri; Karlsson, Linnea; Paunio, Tiina; Karlsson, Hasse 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Polygenic risk scores for major depressive disorder (PRS-MDD) have been identified in large genome-wide association studies, and recent findings suggest that PRS-MDD might interact with environmental risk factors to shape human limbic brain development as early as in the prenatal period. Striatal structures are crucially involved in depression; however, the association of PRS-MDD with infant striatal volumes is yet unknown. In this study, 105 Finnish mother-infant dyads (44 female, 11-54 days ol... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - brain development; Gene-environment interaction; MRI; prenatal programming; striatum; BRAIN; DIMORPHISM; ABNORMALITIES; SEGMENTATION; PHENOTYPES; IMPUTATION; PREGNANCY; SYMPTOMS; HORMONES; DISEASE; 3112 Neurosciences; 3124 Neurology and psychiatry 
N1  -   
PP  -  
ER  -