TY - T1 - Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity SN - / UR - http://hdl.handle.net/10138/332361 T3 - A1 - Fadista, Joao; Kraven, Luke M.; Karjalainen, Juha; Andrews, Shea J.; Geller, Frank; Baillie, J. Kenneth; Wain, Louise; Jenkins, R. Gisli; Feenstra, Bjarke A2 - PB - Y1 - 2021 LA - eng AB - Background: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease, characterized by progressive lung scarring. Severe COVID-19 is associated with substantial pneumonitis and has a number of shared major risk factors with IPF. This study aimed to determine the genetic correlation between IPF and severe COVID-19 and assess a potential causal role of genetically increased risk of IPF on COVID-19 severity. Methods: The genetic correlation between IPF and COVID-19 severity was estimated with ... VO - IS - SP - OP - KW - Mendelian randomization; Covid-19; Idiopathic pulmonary fibrosis; MUC5B; Mucin; 3111 Biomedicine; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -