TY - T1 - Small extracellular vesicles convey the stress-induced adaptive responses of melanoma cells SN - / UR - http://hdl.handle.net/10138/309153 T3 - A1 - Harmati, Maria; Gyukity-Sebestyen, Edina; Dobra, Gabriella; Janovak, Laszlo; Dekany, Imre; Saydam, Okay; Hunyadi-Gulyas, Eva; Nagy, Istvan; Farkas, Attila; Pankotai, Tibor; Ujfaludi, Zsuzsanna; Horvath, Peter; Piccinini, Filippo; Kovacs, Maria; Biro, Tamas; Buzas, Krisztina A2 - PB - Y1 - 2019 LA - eng AB - Exosomes are small extracellular vesicles (sEVs), playing a crucial role in the intercellular communication in physiological as well as pathological processes. Here, we aimed to study whether the melanoma-derived sEV-mediated communication could adapt to microenvironmental stresses. We compared B16F1 cell-derived sEVs released under normal and stress conditions, including cytostatic, heat and oxidative stress. The miRNome and proteome showed substantial differences across the sEV groups and bioi... VO - IS - SP - OP - KW - TUMOR-DERIVED EXOSOMES; SILVER-MODIFIED TIO2; CANCER CELLS; LYMPH-NODES; STEM-CELLS; DOXORUBICIN; CARCINOMA; COMMUNICATION; EXPRESSION; MIGRATION; 3111 Biomedicine; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -