TY  -  
T1  - Small-intestinal TG2-specific plasma cells at different stages of coeliac disease 
SN  -  /  
UR  - http://hdl.handle.net/10138/272539 
T3  -  
A1  - Hietikko, Minna; Koskinen, Outi; Kurppa, Kalle; Laurila, Kaija; Saavalainen, Päivi; Salmi, Teea; Ilus, Tuire; Huhtala, Heini; Kaukinen, Katri; Lindfors, Katri 
A2  -  
PB  - BioMed Central 
Y1  - 2018 
LA  -  
AB  - Abstract
              
                Background
                In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untreated disease. During treatment with a gluten-free diet (GFD), the number of these cells decreases considerably. It has not been previously investigated whether the cells are also present prior to development of villous atrop... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Coeliac disease; Gluten; Transglutaminase 2; Autoantibody; Small intestine 
N1  -   
PP  -  
ER  -