TY  -  
T1  - Spatial immunoprofiling of the intratumoral and peritumoral tissue of renal cell carcinoma patients 
SN  -  /  
UR  - http://hdl.handle.net/10138/340487 
T3  -  
A1  - Bruck, Oscar; Lee, Moon Hee; Turkki, Riku; Uski, Ilona; Penttilä, Patrick; Paavolainen, Lassi; Kovanen, Panu; Järvinen, Petrus; Bono, Petri; Pellinen, Teijo; Mustjoki, Satu; Kreutzman, Anna 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - While the abundance and phenotype of tumor-infiltrating lymphocytes are linked with clinical survival, their spatial coordination and its clinical significance remain unclear. Here, we investigated the immune profile of intratumoral and peritumoral tissue of clear cell renal cell carcinoma patients (n = 64). We trained a cell classifier to detect lymphocytes from hematoxylin and eosin stained tissue slides. Using unsupervised classification, patients were further classified into immune cold, hot... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - UP-REGULATION; EXPRESSION; BLOCKADE; 3111 Biomedicine 
N1  -   
PP  -  
ER  -