TY - T1 - Spermatogonia Loss Correlates with LAMA 1 Expression in Human Prepubertal Testes Stored for Fertility Preservation SN - / UR - http://hdl.handle.net/10138/329356 T3 - A1 - Kurek, Magdalena; Akesson, Elisabet; Yoshihara, Masahito; Oliver, Elizabeth; Cui, Yanhua; Becker, Martin; Alves-Lopes, Joao Pedro; Bjarnason, Ragnar; Romerius, Patrik; Sundin, Mikael; Noren Nystrom, Ulrika; Langenskiold, Cecilia; Vogt, Hartmut; Henningsohn, Lars; Petersen, Cecilia; Soder, Olle; Guo, Jingtao; Mitchell, Rod T.; Jahnukainen, Kirsi; Stukenborg, Jan-Bernd A2 - PB - Y1 - 2021 LA - eng AB - Fertility preservation for male childhood cancer survivors not yet capable of producing mature spermatozoa, relies on experimental approaches such as testicular explant culture. Although the first steps in somatic maturation can be observed in human testicular explant cultures, germ cell depletion is a common obstacle. Hence, understanding the spermatogonial stem cell (SSC) niche environment and in particular, specific components such as the seminiferous basement membrane (BM) will allow progres... VO - IS - SP - OP - KW - germ cells; basal membrane; stem cell niche; seminiferous tubules; infertility; late effects; spermatogonia; Sertoli cells; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -