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T1  - Sphingomyelin and progression of renal and coronary heart disease in individuals with type 1 diabetes 
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UR  - http://hdl.handle.net/10138/324375 
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A1  - FinnDiane Study Grp; Pongrac Barlovic, Drazenka; Harjutsalo, Valma; Sandholm, Niina; Forsblom, Carol; Groop, Per-Henrik 
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Y1  - 2020 
LA  - eng 
AB  - Aims/hypothesis Lipid abnormalities are associated with diabetic kidney disease and CHD, although their exact role has not yet been fully explained. Sphingomyelin, the predominant sphingolipid in humans, is crucial for intact glomerular and endothelial function. Therefore, the objective of our study was to investigate whether sphingomyelin impacts kidney disease and CHD progression in individuals with type 1 diabetes. Methods Individuals (n = 1087) from the Finnish Diabetic Nephropathy (FinnDian... 
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KW  - Albuminuria; Coronary artery disease; Diabetic kidney disease; Glomerular filtration rate; Lipids; NMR metabolomics; Sphingomyelin; KIDNEY-DISEASE; INSULIN-RESISTANCE; SPHINGOLIPID METABOLISM; PLASMA CERAMIDES; ARTERY-DISEASE; ATHEROSCLEROSIS; NEPHROPATHY; INHIBITION; COMPLICATIONS; ASSOCIATION; 3121 General medicine, internal medicine and other clinical medicine 
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