TY - T1 - Structural Diversity of Peptoids : Tube-Like Structures of Macrocycles SN - / UR - http://hdl.handle.net/10138/325433 T3 - A1 - Herlan, Claudine Nicole; Sommer, Katharina; Weis, Patrick; Nieger, Martin; Bräse, Stefan A2 - PB - Y1 - 2021 LA - eng AB - Peptoids, or poly-N-substituted glycines, are characterised by broad structural diversity. Compared to peptides, they are less restricted in rotation and lack backbone-derived H bonding. Nevertheless, certain side chains force the peptoid backbone into distinct conformations. Designable secondary structures like helices or nanosheets arise from this knowledge. Herein, we report the copper-catalysed alkyne-azide cycloaddition (CuAAC) of macrocycles to form innovative tube-like tricyclic peptoids,... VO - IS - SP - OP - KW - peptidomimetics; tricyclic peptoids; CuAAC; foldamers; NANOSHEETS; OLIGOMERS; PEPTIDES; HELICES; WATER; PEPTIDOMIMETICS; GLYCINES); POLYMERS; ORDER; 116 Chemical sciences N1 - PP - ER -