TY  -  
T1  - Structural and Functional Analysis of Coxsackievirus A9 Integrin alpha(v)beta(6) Binding and Uncoating 
SN  -  /  
UR  - http://hdl.handle.net/10138/42728 
T3  -  
A1  - Shakeel, Shabih; Seitsonen, Jani J. T.; Kajander, Tommi; Laurinmaki, Pasi; Hyypia, Timo; Susi, Petri; Butcher, Sarah J. 
A2  -  
PB  -  
Y1  - 2013 
LA  - eng 
AB  - Coxsackievirus A9 (CVA9) is an important pathogen of the Picornaviridae family. It utilizes cellular receptors from the integrin v family for binding to its host cells prior to entry and genome release. Among the integrins tested, it has the highest affinity for v6, which recognizes the arginine-glycine-aspartic acid (RGD) loop present on the C terminus of viral capsid protein, VP1. As the atomic model of CVA9 lacks the RGD loop, we used surface plasmon resonance, electron cryo-microscopy, and i... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - HUMAN PARECHOVIRUS 1; 3-DIMENSIONAL RECONSTRUCTION; ENTEROVIRUS INFECTIONS; VITRONECTIN RECEPTOR; ELECTRON-MICROSCOPY; CRYSTAL-STRUCTURE; VIRUS-INFECTION; RESOLUTION; ENTRY; IMAGE; 1183 Plant biology, microbiology, virology 
N1  -   
PP  -  
ER  -