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T1  - Structural and functional alterations in the brain gray matter among first-degree relatives of schizophrenia patients : A multimodal meta-analysis of fMRI and VBM studies 
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UR  - http://hdl.handle.net/10138/329954 
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A1  - Saarinen, Aino I. L.; Huhtaniska, Sanna; Pudas, Juho; Björnholm, Lassi; Jukuri, Tuomas; Tohka, Jussi; Granö, Niklas; Barnett, Jennifer H.; Kiviniemi, Vesa; Veijola, Juha; Hintsanen, Mirka; Lieslehto, Johannes 
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Y1  - 2020 
LA  - eng 
AB  - Objective: We conducted a multimodal coordinate-based meta-analysis (CBMA) to investigate structural and functional brain alterations in first-degree relatives of schizophrenia patients (FRs). Methods: We conducted a systematic literature search from electronic databases to find studies that examined differences between FRs and healthy controls using whole-brain functional magnetic resonance imaging (fMRI) or voxel-based morphometry (VBM). A CBMA of 30 fMRI (754 FRs; 959 controls) and 11 VBM (88... 
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KW  - Schizophrenia; Psychosis; Genetic risk; Familial risk; Brain structure; Brain activity; VOXEL-BASED MORPHOMETRY; INFERIOR FRONTAL GYRUS; SPATIAL WORKING-MEMORY; FAMILIAL HIGH-RISK; UNAFFECTED RELATIVES; INTERMEDIATE PHENOTYPE; RESPONSE-INHIBITION; PREFRONTAL CORTEX; GENETIC LIABILITY; TEMPORAL GYRUS; 3124 Neurology and psychiatry 
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