TY - T1 - Surge of Peripheral Arginine Vasopressin in a Rat Model of Birth Asphyxia SN - / UR - http://hdl.handle.net/10138/233470 T3 - A1 - Summanen, Milla; Back, Susanne; Voipio, Juha; Kaila, Kai A2 - PB - Y1 - 2018 LA - eng AB - Mammalian birth is accompanied by a period of obligatory asphyxia, which consists of hypoxia (drop in blood O-2 levels) and hypercapnia (elevation of blood CO2 levels). Prolonged, complicated birth can extend the asphyxic period, leading to a pathophysiological situation, and in humans, to the diagnosis of clinical birth asphyxia, the main cause of hypoxic-ischemic encephalopathy (HIE). The neuroendocrine component of birth asphyxia, in particular the increase in circulating levels of arginine v... VO - IS - SP - OP - KW - arginine vasopressin (AVP); copeptin; birth asphyxia; hypothalamic-pituitary axis (HPA axis); blood gases; base deficit; perinatal; neonatal; PARAVENTRICULAR NUCLEUS; COPEPTIN; BRAIN; HYPOXIA; STRESS; ENCEPHALOPATHY; HYPOTHALAMUS; PRECURSOR; RELEASE; NEURONS; 3112 Neurosciences; 3124 Neurology and psychiatry N1 - PP - ER -