TY - T1 - Synthesis, Stability and Relaxivity of TEEPO-Met : An Organic Radical as a Potential Tumour Targeting Contrast Agent for Magnetic Resonance Imaging SN - / UR - http://hdl.handle.net/10138/237278 T3 - A1 - Soikkeli, Maiju; Horkka, Kaisa; Moilanen, Jani O.; Timonen, Marjut; Kavakka, Jari; Heikkinen, Sami A2 - PB - Y1 - 2018 LA - eng AB - Cancer is a widespread and life-threatening disease and its early-stage diagnosis is vital. One of the most effective, non-invasive tools in medical diagnostics is magnetic resonance imaging (MRI) with the aid of contrast agents. Contrast agents that are currently in clinical use contain metals, causing some restrictions in their use. Also, these contrast agents are mainly non-specific without any tissue targeting capabilities. Subsequently, the interest has notably increased in the research of ... VO - IS - SP - OP - KW - nitroxides; radicals; methionine; contrast agents; MRI; NMR; EPR; SPIN-LABEL; IN-VITRO; NITROXIDES; REDUCTION; TRANSPORT; GLUCOSE; 3126 Surgery, anesthesiology, intensive care, radiology; 116 Chemical sciences; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -