TY - T1 - Testicular Function and Bone in Young Men with Severe Childhood-Onset Obesity SN - / UR - http://hdl.handle.net/10138/241067 T3 - A1 - Laakso, Saila; Viljakainen, Heli; Lipsanen-Nyman, Marita; Turpeinen, Ursula; Ivaska, Kaisa K.; Anand-Ivell, Ravinder; Ivell, Richard; Mäkitie, Outi A2 - PB - Y1 - 2018 LA - eng AB - Background: Previous studies suggest increased risk for hypoandrogenism and fractures in men with obesity. We aimed to describe the effects of severe childhood-onset obesity on the cross talk between metabolic state, testes, and skeleton at late puberty. Methods: A cohort of adolescent and young adult males with severe childhood-onset obesity (n = 21, mean age 18.5 years) and an age-matched control group were assessed for testicular hormones and X-ray absorptiometry-derived bone mass. Results: C... VO - IS - SP - OP - KW - Boys; Metabolism; Sex hormones; Puberty; Testosterone; INSULIN-LIKE FACTOR-3; MALE-ADOLESCENTS; MINERAL DENSITY; PUBERTAL DEVELOPMENT; OSTEOCALCIN; TESTOSTERONE; CHILDREN; ADULTS; BOYS; SERUM; 3123 Gynaecology and paediatrics; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -