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T1  - The Acute Effects of LSD on Reward Behavior in Mice with Intracranial Self-Stimulation 
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UR  - URN:NBN:fi:hulib-202011114451; http://hdl.handle.net/10138/321354 
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A1  - Harkki, Juliana Sade Maria 
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PB  - Helsingin yliopisto 
Y1  - 2020 
LA  - eng 
AB  - Background: Alcohol dependence is a chronic severe substance use disorder that has devastating personal and public health consequences. The efficacy of the current pharmacotherapy options for the treatment of alcohol dependence are modest at best, therefore better alternatives are greatly needed.
Lysergic acid diethylamide (LSD) has shown promise in treatment of alcohol dependence in several clinical trials. A sigle high dose of LSD has been suggested to have a treatment effect that last for at... 
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KW  - 5-HT2A; 5-HT2C; addiction; alcohol dependence; amphetamine; ethanol; intracranial self-stimulation; lipopolysaccharide; lysergic acid diethylamide; reward circuitry; alcoholism; Neuroscience and psychobiology; Neuroscience and psychobiology; Neuroscience and psychobiology; Translationaalisen lääketieteen maisteriohjelma (Translational Medicine); Master's Programme in Translational Medicine; Magisterprogrammet i translationell medicin 
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