TY - T1 - The Effect of Donor Age and Recipient Characteristics on Renal Outcomes in Patients Receiving Prolonged-Release Tacrolimus After Liver Transplantation : Post-Hoc Analyses of the DIAMOND Study SN - / UR - http://hdl.handle.net/10138/305159 T3 - A1 - DIAMOND Study Grp; Trunecka, Pavel; Klempnauer, Juergen; Bechstein, Wolf Otto; Isoniemi, Helena; Tisone, Giuseppe A2 - PB - Y1 - 2019 LA - eng AB - Background: The DIAMOND study of de novo liver transplant patients showed that prolonged-release tacrolimus exposure in the acute post-transplant period maintained renal function over 24 weeks of treatment. To assess these findings further, we performed a post-hoc analysis in patients according to baseline kidney function, Model for End-stage Liver Disease [MELD] scores, and donor age. Material/Methods: Patients received prolonged-release tacrolimus (initial-dose, Arm 1: 0.2 mg/kg/day, Arm 2: 0.... VO - IS - SP - OP - KW - Glomerular Filtration Rate; Immunosuppressive Agents; Liver Transplantation; Tacrolimus; ACUTE KIDNEY INJURY; RISK-FACTORS; DYSFUNCTION; FAILURE; MORTALITY; MELD; 3126 Surgery, anesthesiology, intensive care, radiology N1 - PP - ER -