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T1  - The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System 
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UR  - http://hdl.handle.net/10138/319292 
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A1  - Daryabor, Gholamreza; Atashzar, Mohamad Reza; Kabelitz, Dieter; Meri, Seppo; Kalantar, Kurosh 
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Y1  - 2020 
LA  - eng 
AB  - Metabolic abnormalities such as dyslipidemia, hyperinsulinemia, or insulin resistance and obesity play key roles in the induction and progression of type 2 diabetes mellitus (T2DM). The field of immunometabolism implies a bidirectional link between the immune system and metabolism, in which inflammation plays an essential role in the promotion of metabolic abnormalities (e.g., obesity and T2DM), and metabolic factors, in turn, regulate immune cell functions. Obesity as the main inducer of a syst... 
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KW  - immunometabolism; infectious diseases; insulin resistance; obesity; systemic low-level inflammation; SARS-CoV-2; type 2 diabetes mellitus; GLYCATION END-PRODUCTS; RESPIRATORY SYNDROME CORONAVIRUS; ISLET AMYLOID POLYPEPTIDE; INNATE LYMPHOID-CELLS; PANCREATIC BETA-CELLS; NF-KAPPA-B; ENDOTHELIAL-CELLS; OXIDATIVE STRESS; INSULIN-RESISTANCE; T-CELL; 3121 General medicine, internal medicine and other clinical medicine 
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