TY  -  
T1  - The Gut-Kidney Axis : Putative Interconnections Between Gastrointestinal and Renal Disorders 
SN  -  /  
UR  - http://hdl.handle.net/10138/248097 
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A1  - Lehto, Markku; Groop, Per-Henrik 
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PB  -  
Y1  - 2018 
LA  - eng 
AB  - Diabetic kidney disease (DKD) is a devastating condition associated with increased morbidity and premature mortality. The etiology of DKD is still largely unknown. However, the risk of DKD development and progression is most likely modulated by a combination of genetic and environmental factors. Patients with autoimmune diseases, like type 1 diabetes, inflammatory bowel disease, and celiac disease, share some genetic background. Furthermore, gastrointestinal disorders are associated with an incr... 
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KW  - type 1 diabetes; diabetic nephropathy; chronic kidney disease; gut permeability; inflammatory bowel disease; gastrointestinal inflammation; contact activation; intestinal alkaline phosphatase; INFLAMMATORY-BOWEL-DISEASE; INTESTINAL ALKALINE-PHOSPHATASE; FECAL MICROBIOTA TRANSPLANTATION; TYPE-1 DIABETES-MELLITUS; KALLIKREIN-KININ SYSTEM; GENETICALLY SUSCEPTIBLE RATS; NORMAL C1 INHIBITOR; DSS-INDUCED COLITIS; HEREDITARY ANGIOEDEMA; CELIAC-DISEASE; 3121 General medicine, internal medicine and other clinical medicine 
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