TY  -  
T1  - The Potential Role of Matrix Metalloproteinases 8 and 9 and Myeloperoxidase in Predicting Outcomes of Bacterial Meningitis of Childhood 
SN  -  /  
UR  - http://hdl.handle.net/10138/308550 
T3  -  
A1  - Savonius, Okko; Roine, Irmeli; Alassiri, Saeed; Tervahartiala, Taina; Helve, Otto; Fernandez, Josefina; Peltola, Heikki; Sorsa, Timo; Pelkonen, Tuula 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Background. Matrix metalloproteinases (MMPs) and myeloperoxidase (MPO) contribute to the inflammatory cascade in the cerebrospinal fluid (CSF) during bacterial meningitis. We determined levels of MPO, MMP-8, MMP-9, and tissue inhibitor of metalloproteinase- (TIMP-) 1 in the CSF of children with bacterial meningitis and investigated how these inflammatory mediators relate to each other and to the disease outcomes. Methods. Clinical data and the diagnostic CSF samples from 245 children (median age... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - CEREBROSPINAL-FLUID; ACTIVATION; MMP-9; MATRIX-METALLOPROTEINASE-9; INFLAMMATION; INHIBITORS; TIMP-1; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -